| Cover | 1 |
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| Title Page | 4 |
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| Copyright | 5 |
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| Table of Contents | 6 |
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| Body | 10 |
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| Foreword | 10 |
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| I. Genes and society | 12 |
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| A silent cognitive revolution | 12 |
| Well meant | 13 |
| Mentally disabled, even before birth? | 14 |
| Three times 21 | 15 |
| Has our society decided? | 16 |
| Down’s Heritage | 18 |
| 47 chromosomes rather than 46 | 19 |
| Mutations | 20 |
| Eugenics, compulsory sterilization and euthanasia | 21 |
| Fear of low IQ | 23 |
| Genetics and epigenetics | 24 |
| A picture is worth a thousand words | 25 |
| Summary | 27 |
| II. The brain and intelligence | 28 |
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| Head size and intelligence tests | 28 |
| IQ as gatekeeper | 30 |
| Why being different is normal | 31 |
| Am I stupid? | 33 |
| Genes for brain growth or stress in early childhood? | 34 |
| Brain growth and evolution | 36 |
| Birdbrained geniuses | 37 |
| The human brain is a social tool | 38 |
| The brain as a learning tool | 40 |
| Accelerating thinking through abstraction | 41 |
| Mouse memory | 42 |
| The seat of learning | 44 |
| Memory is distributed across the brain | 46 |
| Summary | 47 |
| III. Neurotransmitters and neuroenhancement | 49 |
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| Enzymes: catalysts in the brain | 49 |
| Acetylcholine and the fear of Alzheimer’s | 51 |
| Donepezil: doping for the brain | 53 |
| How the brain neutralizes medication | 55 |
| Dopamine: addictive stimulation | 56 |
| Glutamate: more than just a matter of taste | 58 |
| Memantine: hope for a learning pill | 59 |
| GABA: inhibit inhibition | 61 |
| Basmisanil: release the brakes in the brain | 62 |
| Brain doping: cleverer by prescription? | 63 |
| Neuroenhancement or essential drug? | 65 |
| Summary | 66 |
| IV. Neurodiversity and attention | 67 |
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| Serotonin, an endogenous antidepressant | 67 |
| Oxytocin: cuddling depression away | 69 |
| Norepinephrine: rock ‘n’ roll in the brain | 70 |
| Humans are different and mice too | 72 |
| Neurodiversity instead of neurodegeneration | 73 |
| Removing the fear of aging | 75 |
| Studying at university with trisomy 21? | 76 |
| Learning from rabbis and nuns | 77 |
| Segregation already begins with speech | 79 |
| Empathy for neurodiversity | 80 |
| Motor learning and the 21st chromosome | 82 |
| Acetylcholine in the striate body | 84 |
| Emotion and the 21st chromosome | 85 |
| Short-term memory and the 21st chromosome | 87 |
| Learning in sleep | 89 |
| At the focal point of the stream of thoughts | 91 |
| The bifurcation diagram: calculation and hypothesis | 93 |
| Summary | 96 |
| V. Attention and memory | 97 |
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| Navon figures | 97 |
| The overall shape and details | 100 |
| Dice-pip and interference images | 103 |
| Abstraction means “draw away from …” | 107 |
| The scope of attention | 110 |
| The magical number four | 111 |
| Measuring the scope of attention | 113 |
| Memory and matching pairs | 117 |
| Reveal the numbers in sequence | 121 |
| Object permanence | 123 |
| Observe and remember causalities | 124 |
| Abstract thought in the pushchair | 127 |
| Mouse and duck theater | 128 |
| Supersigns and abstraction | 132 |
| Summary | 134 |
| VI. Imitation and motor learning | Alfred Christoph Röhm | 136 |
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| Juggling in a small attention window | 136 |
| Auditory and haptic scope of attention | 137 |
| Proprioception – endogenous perception | 139 |
| Scope of attention for proprioception | 141 |
| Body percussion | 142 |
| Successful imitation depends on the number of micromotions | 144 |
| Dialogic learning requires creativity | 145 |
| Summary | 146 |
| VII. Speech and thought | Kim Lena Hurtig-Bohn | 148 |
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| The window to a child’s head | 148 |
| The prefrontal cortex and private speech | 149 |
| The development of private speech in childhood | 151 |
| Private speech in pedagogy | 152 |
| The zone of proximal development | 153 |
| Private speech and trisomy 21 | 154 |
| Private speech in autism spectrum disorders | 156 |
| Summary | 157 |
| VIII. Cognitive development and mathematics | Torben Rieckmann | 159 |
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| Trisomy 21 and mathematics? | 159 |
| Trisomy 21 and dyscalculia | 160 |
| Clustering and supersigns | 162 |
| The power of five | 166 |
| Deliberately use teaching materials | 168 |
| Appropriate visual aids | 171 |
| Summary | 175 |
| IX. Communication and emotion | Angela Kalmutzke | 176 |
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| It’s great that you have a child with Down syndrome! | 176 |
| Respect for the essence of and confidence in learning ability | 178 |
| On life and death | 180 |
| Late termination of pregnancy | 182 |
| Opting for life | 184 |
| The social matrix | 185 |
| Behavioral problems today, personality disorders tomorrow? | 189 |
| Promoting self-worth | 192 |
| Summary | 196 |
| Afterword | 197 |
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| Literature | 201 |