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Masamichi Kamihira, Yoshinori Katakura, Akira Ito
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Masamichi Kamihira, Yoshinori Katakura, Akira Ito
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Basic and Applied Aspects Proceedings of the 21st Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT), Fukuoka, Japan, November 24-27, 2008
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Springer-Verlag
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9789048138920
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1
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CHF 279.00
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Animal cell technology is a growing discipline of cell biology which aims not only to understand the structure, function and behavior of differentiated animal cells, but also to ascertain their ability to be used for industrial and medical purposes. Some of the major goals of animal cell technology include: the clonal expansion of differentiated cells, the optimization of their culture conditions, modulation of their ability for the production of medically and pharmaceutically important proteins and the application of animal cells to gene therapy, artificial organs and functional foods. This volume gives the readers a complete review of the present state-of-the-art research in Japan and other countries where this field is well advanced. The Proceedings will be useful to cell biologists, biochemists, molecular biologists, immunologists, biochemical engineers and to those working in either academic environments or in the biotechnology and pharmacy industries related to animal cell culture.
Preface 6 Contents 8 Contributors 16 Purification of Hepatoblasts from Fetal Mouse Livers by Using a Temperature- Reversible Gelation Polymer and Their Application in Regenerative Medicine 32 Computer Aided Rational Design of Biochemical Systems 38 DNA Microarray in Nutrigenomics and Cancer Prevention Research: Elucidating Molecular Signatures of Cancer Preventive Phytochemicals 44 DNA Microarray Technology Evaluation of Effect of Dietary Intake of Crude Rice Glycosphingolipids in Mice 50 Integrated Pathway Analysis of Genome-Wide Expression Changes Associated with Serum- Free Suspension Adaptation of an Antibody- Producing Chinese Hamster Ovary ( CHO) Cell Line 57 Affordable Mab by Ensuring Low Cog 63 Evaluation of Neurotoxicity of Environmental Chemicals Using Neural Stem Cells and Neuroblastoma Cells 70 Integration of Endothelial Cell-Covered Hepatocyte Spheroids for Construction of Vascularized Liver Tissue 74 Characterization of Cell-Sized Vesicles Induced from Human Lymphoid Cell Lines 80 Dendrimer-Immobilized Culture Surface as a Tool to Promote Aggregate Formation of Anchorage- Dependent Cells 85 Advantage of Alagln as an Additive to Cell Culture Medium 92 Supplementation of Phosphatidylcholine Protects the Hybridoma Cells from Apoptosis Induced by SerumWithdrawal 99 Monoclonal Antibody Productivity of Hybridoma Cells Under Active Hypothermic Growth Condition 103 Efficient Selection of Cell Clones with Higher Productivity in the Production of Recombinant Human Monoclonal Antibodies 108 Continuous Cell Production from Three Dimensional Hematopoietic Microenvironment in Polyurethane Foam 114 A New Approach for Drug Discovery and Differentiation Study Using Cutting-Edge 3d Cell Culture System 120 Dimensional Cell Culture Dish for In Vivo-Like Cell Culture 128 Characterization of the Erythropoietin (EPO) Protein Production in the Recombinant Human Cultured Cells, in which the Exogenous EPO Gene was Introduced into Hypoxanthine Phosphoribosyl Transferase ( HPRT) Gene Locus 134 Development of Protein High Expression System by Using Fructose Metabolism 140 Controlling Fucosylation Levels of Antibodies with Osmolality during Cell Culture 145 Comparison of Immunoresponses Between Cecal Patch Cells and PeyerÌs Patch Cells Stimulated by Bacterial Components 150 Conjugate of ß-Lactoglobulin with Carboxymethyl Dextran Increased the Antigen- Specific IgG1 Production, While It Decreased IgE Production Compared with Native ß- Lactoglobulin 155 Anti-Inflammatory Action of Epigallocatechin- 3- Gallate at a Physiological Concentration through the 67- KDA Laminin Receptor in Lipopolysaccharide- Stimulated Raw264.7 Cells 160 Enhancement of Antibody Production using Solution after Antibody Purification: Application of Spent Medium for Antibody Production 166 Production of Human Monoclonal Antibodies Against FC Epsilon Receptor I Alpha by Combining In Vitro Immunization with Phage Display 172 Enhancement of Hepatocyte Function Through Heterotypic Cell- Cell Interactions Using E- Cadherin- Expressing NIH3T3 Cells 179 Magnetic Cell-Patterning for Tissue Engineering 184 Magnetic Force-Based Tissue Engineering of Skeletal Muscle for Bio- Actuator 190 Fabrication of Skeletal Muscle Tissue from C2C12 Myoblast Cell Towards the Use as Bio- Actuator 196 Retroviral Vectors Pseudotyped with Chimeric Vesicular Stomatitis Virus Glycoprotein for Antibody- Dependent Gene Transduction 203 Improvement of CPP-RBD for siRNA Delivery 209 Production of Recombinant Human EPO and EPO/ Fc Fusion Proteins by Chinese Hamster Ovary Cells 215 Development of Oviduct-Specific Gene Expression System for Transgenic Avian Bioreactor 221 Production of Therapeutic Proteins Composed of Seven Dominant Human T Cell Epitopes Derived from the Japanese Cedar Pollen Allergens 227 The Differentiation of C2C12 Cells to Myotube by Paraquat 233 Molecular Cloning and Characterization of a Novel Canine Sulfotransferase 238 In Vitro Analysis of the Interaction Between Human Intestinal Epithelial Cells and Macrophage- Like Cells 247 Role of Ubiquitination Promoted During Restimulation in the Induction of T CellAnergy 253 Expressio
