| Preface | 7 |
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| Contents | 10 |
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| Introduction | 13 |
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| What is simulation? | 13 |
| What is DASE? | 19 |
| DASE symbols and terms | 22 |
| Solutions for exercises | 24 |
| Low-order polynomial regression metamodels and their designs: basics | 26 |
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| Introduction | 27 |
| Linear regression analysis: basics | 30 |
| Linear regression analysis: first-order polynomials | 38 |
| First-order polynomial with a single factor | 38 |
| First-order polynomial with several factors | 39 |
| Designs for first-order polynomials: resolution-III | 47 |
| 2k-p designs of resolution-III | 47 |
| Plackett-Burman designs of resolution-III | 50 |
| Regression analysis: factor interactions | 51 |
| Designs allowing two-factor interactions: resolution-IV | 53 |
| Designs for two-factor interactions: resolution-V | 57 |
| Regression analysis: second-order polynomials | 60 |
| Designs for second-degree polynomials: Central Composite Designs (CCDs) | 61 |
| Optimal designs and other designs | 62 |
| Validation of metamodels | 65 |
| Coefficients of determination and correlation coefficients | 65 |
| Cross-validation | 68 |
| More simulation applications | 74 |
| Conclusions | 77 |
| Appendix: coding of nominal factors | 77 |
| Solutions for exercises | 80 |
| Classic assumptions revisited | 83 |
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| Introduction | 83 |
| Multivariate simulation output | 84 |
| Designs for multivariate simulation output | 87 |
| Nonnormal simulation output | 88 |
| Realistic normality assumption? | 88 |
| Testing the normality assumption | 89 |
| Transformations of simulation I/O data, jackknifing, and bootstrapping | 90 |
| Heterogeneous simulation output variances | 97 |
| Realistic constant variance assumption? | 97 |
| Testing for constant variances | 98 |
| Variance stabilizing transformations | 99 |
| LS estimators in case of heterogeneous variances | 99 |
| Designs in case of heterogeneous variances | 102 |
| Common random numbers (CRN) | 103 |
| Realistic CRN assumption? | 104 |
| Alternative analysis methods | 104 |
| Designs in case of CRN | 106 |
| Nonvalid low-order polynomial metamodel | 107 |
| Testing the validity of the metamodel | 107 |
| Transformations of independent and dependent regression variables | 108 |
| Adding high-order terms to a low-order polynomial metamodel | 108 |
| Nonlinear metamodels | 109 |
| Conclusions | 109 |
| Solutions for exercises | 110 |
| Simulation optimization | 111 |
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| Introduction | 111 |
| RSM: classic variant | 115 |
| Generalized RSM: multiple outputs and constraints | 120 |
| Testing an estimated optimum: KKT conditions | 126 |
| Risk analysis | 133 |
| Latin Hypercube Sampling (LHS) | 136 |
| Robust optimization: Taguchian approach | 140 |
| Case study: Ericsson's supply chain | 145 |
| Conclusions | 147 |
| Solutions for exercises | 148 |
| Kriging metamodels | 149 |
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| Introduction | 149 |
| Kriging basics | 150 |
| Kriging: new results | 157 |
| Designs for Kriging | 159 |
| Predictor variance in random simulation | 161 |
| Predictor variance in deterministic simulation | 162 |
| Related designs | 164 |
| Conclusions | 165 |
| Solutions for exercises | 166 |
| Screening designs | 167 |
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| Introduction | 167 |
| Sequential Bifurcation | 170 |
| Outline of simplest SB | 170 |
| Mathematical details of simplest SB | 175 |
| Case study: Ericsson's supply chain | 177 |
| SB with two-factor interactions | 179 |
| Conclusions | 181 |
| Solutions for exercises | 182 |
| Epilogue | 183 |
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| References | 185 |
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| Index | 221 |