| Preface | 5 |
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| Acknowledgments | 9 |
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| Contents | 10 |
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| Contributors | 13 |
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| I THE COLUMBUS CONCEPT: SCOPE AND LIMITATION | 16 |
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| Wild-Type Land-Based Food in Health Promotion and Disease Prevention | 17 |
| The Japanese Experience | 35 |
| High .6:.3 Fatty Acid Ratio | 43 |
| Omega-6/Omega-3 Fatty Acid Ratio is Important for Health | 49 |
| Tissue Omega-6 and Omega-3 Fatty Acids in Health and Disease | 64 |
| w-3 Fatty Acids and the Risk of Coronary Heart Disease | 67 |
| The Nutritional Conditions of Human Evolution | 86 |
| II ESSENTIAL NUTRIENTS IN THE WILD: HEALTH BENEFITS | 99 |
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| The “ Wild-Type” Egg | 100 |
| The Essentiality of Eicosapentaenoic Acid in Breast Milk During Human Lactation | 123 |
| The Natural Fatty Acid Compositions of Eggs of Wild Birds and the Consequences of Domestication | 129 |
| Simultaneous Enrichment of Eggs With PUFAs and Antioxidants | 146 |
| Egg Composition vs CVD Risk | 161 |
| Omega-3 Fatty Acids | 174 |
| Chia as a New Source of w-3 Fatty Acids | 183 |
| Evaluating the Biological Activity and Effects on Human Health of Fish Oil and Its Omega- 3 Fatty Acids | 199 |
| Omega- 3 Fatty Acids and Mediterranean Diet in the Prevention and Treatment of Cardiovascular Diseases | 219 |
| Dietary Prevention of Coronary Heart Disease | 230 |
| Fatty Acids, Insulin Resistance and Diabetes | 246 |
| Fatty Acids in the Causation and Therapy of Metabolic Syndrome | 265 |
| Immune Modulation and Cancer Resistance | 287 |
| w-3 Fatty Acids in Physical and Mental Health and Disease | 310 |
| Dietary Prevention of Adult Macular Degeneration | 323 |
| Promoting Eye and Skin Health Through Intake of the Natural Carotenoid Lutein | 330 |
| Calcium Phosphate | 342 |
| III FUNCTIONAL COMPONENTS IN THE WILD: HEALTH BENEFITS | 353 |
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| Natural Antioxidants in Land- and Marine- Based Wild- Type Food | 354 |
| Chia Seeds and the Columbus Concept | 373 |
| Health Effects of Foods Rich in Polyphenols | 389 |
| Polyphenols and Immunity | 409 |
| Flavonoid-Rich Dietary Supplements’ Influence on Heart Failure | 431 |
| Dietary Carotenoids in Health Promotion | 439 |
| Dietary Intake of Lycopene and Risk of Prostate Cancer | 459 |
| IV WILD-TYPE FOOD IN DIFFERENT CULTURES: HEALTH BENEFITS | 464 |
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| Local Wild Foods in the Mediterranean Countries | 465 |
| Changing the Spanish-Mediterranean Diet | 473 |
| Lebanese Traditional Diets and Health Effects | 486 |
| Fats and Fatty Acids in Nutrition of the Iranian People | 492 |
| Southeast Asian Diets and Health Promotion | 508 |
| V THE COLUMBUS CONCEPT: THE MARKET APPROACH | 527 |
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| Columbus Feed Around the World | 528 |
| Modification of a National Diet and Lifestyle Toward Wild- Type Foods | 536 |
| Studies on the Effects of Diets Realistic for Westernized People on Plasma Lipoprotein Composition, Metabolism, and Atherosclerosis in Vervet Monkeys | 546 |
| Index | 556 |